• Clonidine

    Clonidine (Catapres, Duraclon, Kapvay) is moderately effective in treating hyperactivity and irritability in children with ASDs. Clonidine may be helpful for sleep initiation and maintenance, specifically for reducing sleep initiation latency (SOL) which is the length of time that it takes to accomplish the transition from full wakefulness to sleep, and to prevent night awakening, hyperactivity and irritability.

    Doses range from 0.1 to 0.2 mg/day.

    Side effects may include drowsiness, sedation, and decreased activity.

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