Fluoxetine (Prozac, Rapiflux, Reconcile, Sarafem, Selfemra)
Larger studies of fluoxetine have not found it to be effective in the treatment of repetitive behaviors in children. The drug has proven to be more effective in adults and adolescents with autism. Adults show reductions in repetitive behaviors, obsessive-compulsive symptoms, and temper outbursts with fluoxetine. The Study of Fluoxetine in Autism (SOFIA), the largest double-blind, placebo-controlled trial of an SRI in children with autism to date, concluded that fluoxetine is not effective for the treatment of repetitive behaviors in children.
Fluoxetine normal doses are 20 to 80 mg/day.
Side effects may include hypomania (irritability or euphoria), and increased aggression.