In children and adolescents, haloperidol has been demonstrated to be efficacious in the short and long-term treatment of symptoms associated with autism. In adults, haloperidol is superior to clomipramine in the management of irritability. Older children respond more favorably to haloperidol compared with younger children.
It has shown effective in reducing repetitive movements such as rocking and arm flapping (“stereotypies”), social withdrawal and improved orientation and decreased maladaptive behaviors such as irritability, mood swings and uncooperativeness.
Doses range between 0.5 to 4.0 mg per day.
Haloperidol is generally well tolerated.