• Olanzapine

    Olanzapine (Zyprexa) is moderately effective in children with ASDs and has demonstrated some effectiveness in adults, but the side effects of increased appetite, weight gain, and sedation are very common.

    Olanzapine has demonstrated improvements in motor restlessness or hyperactivity, social relatedness, affectual reactions, sensory responses, language usage, SIB, aggression, irritability or anger, anxiety, and depression, but have shown no changes in reduction of repetitive behaviors.

    Doses range from 2.5 to 20 mg/day.

    Side effects of increased appetite, weight gain, sedation, and loss of strength are very common.

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